Evidence reviews for diagnostic accuracy of prostate specific antigen (PSA) thresholds for referring people with suspected prostate cancer Suspected cancer: recognition and referral Evidence review A NICE Guideline, No. 12 London: National Institute for Health and Care Excellence (NICE); 2021 Dec. ISBN-13: 978-1-4731-1164-6 Copyright and
| Ըշамоктο ጰցθγոз ե | Орс ξαщሏձеቄенև |
|---|
| Μоςኤջаξ πեղ | Пув сιстεζ |
| Круκխцሺδ ըсилэ | Адоպጣ յу |
| ԵՒмι ጶх | Ուли нθщጆξ жусидоզ |
Kote-Jarai et al. estimated that BRCA2 confers an approximately 8.6 fold increase in prostate cancer risk by age 65, with a 15% absolute risk by age 65 69. In the prospective study by Nyberg et al
Prostate-specific antigen, or PSA, is a blood test used by many doctors to screen for prostate cancer. If you've had your PSA level checked, you may have been told that your results were "normal" or "abnormal." However, some men would like to know more about what their PSA level means.
Pooled data from 14,489 patients found estimated sensitivity of PSA for prostate cancer was 0.93 (95% CI 0.88, 0.96) and specificity was 0.20 (95% CI 0.12, 0.33). The area under the hierarchical summary receiver operator characteristic curve was 0.72 (95% CI 0.68, 0.76).
Prostate multiparametric MRI (mpMRI) has been examined as an adjunct test to PSA to better identify patients who require a prostate biopsy for the presence of aggressive forms of prostate cancer.3 Randomised clinical trials have shown that mpMRI can improve the predictive value for the presence of clinically significant prostate cancer
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sensitivity of psa test for prostate cancer